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Most daratumumab infusion reactions occur in first infusion
The high rate of infusion-related reactions at first daratumumab infusion may be related to treatment duration, based on data from the CASTOR and...
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Biosimilar matches rituximab in large follicular lymphoma trial
MADRID – The biosimilar GP2013 met the criteria for therapeutic equivalence to rituximab in a large comparator trial of previously untreated...
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Alternating therapy in renal cell carcinoma fails to show an advantage
Everolimus alternating with pazopanib and pazopanib alone were compared in a randomized, multicenter controlled trial.
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Genetic advances push personalization of cancer prevention
BOSTON – Personalized medicine is expanding to take on the challenges of colorectal cancer prevention.
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Orbital, over rotational, atherectomy holds survival edge in elderly, obese
Orbital atherectomy was associated with better survival than rotational atherectomy in elderly and obese patients requiring percutaneous...
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Liver disease likely to become increasing indication for bariatric surgery
Bariatric surgery is effective for treatment of fatty liver disease, showing a 90% improvement in steatosis.
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Doubt expressed about potential of any single regimen to treat all hep C
PHILADELPHIA – Individualized care and follow-up will still be needed to treat HCV.
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Of six milestones, only two left on route to hep B cure
PHILADELPHIA – As in hepatitis C, it is likely a combination of therapies will be essential to achieve eradication of hep B and infection cure.
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Three clinical disorders confound diagnosis of gastroparesis
A detailed history should be taken before advanced diagnostic tests are ordered.
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Therapeutic window is narrow for steroids in alcoholic hepatitis
PHILADELPHIA – The main lesson for discordant data regarding the benefit of corticosteroids for alcoholic hepatitis is that mortality reductions...
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Liver disease likely to become increasing indication for bariatric surgery
Bariatric surgery is effective for treatment of fatty liver disease, showing a 90% improvement in steatosis.
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PPI-responsive eosinophilic esophagitis may be misnomer
Proton pump–inhibitor benefit in EoE is now thought to be acid independent.
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TAVR can be performed safely within 30 days of PCI
WASHINGTON – Recent percutaneous coronary intervention should not deter CAD patients from undergoing TAVR.
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Arteriovenous coupler for structural hypertension poised for sham-controlled study
WASHINGTON – A new device may be the best opportunity yet to achieve sustained blood pressure control in individuals aged 60 years and older,...
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When STEMI door-to-balloon times deteriorate
WASHINGTON – With small deviations in process over time, delays build in the emergency treatment of ST segment elevation MI.