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Legacy of neutral renal denervation trial recast by long-term outcomes: SYMPLICITY HTN-3
Although interest in renal denervation in hypertension fell off after disappointing results from the 2014 trial, a new, longer-term analysis...
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PASCAL for MV repair noninferior to MitraClip in CLASP IID; FDA took notice
A newly FDA-approved transcatheter mitral valve repair system and another one widely used for years were similarly safe and effective in an...
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Ultrasonic renal denervation passes 2-month test in uncontrolled HTN: RADIANCE II
No ill effects were seen in the sham-controlled trial of patients with uncontrolled mild to moderate hypertension. The approach led to significant...
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Heparin pretreatment may safely open arteries before STEMI cath
The “early reperfusion” associated with IRA patency at angiography “could have long-term benefit due to smaller infarct size.”
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No invasive strategy benefit at 5 years in ISCHEMIA-CKD extension study
The trial speaks to the lofty high-risk status of patients with CAD. ‘You’re seeing in a group of patients, with largely preserved EF but advanced...
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Vintage drug atop IV loop diuretics boosts decongestion in ADHF: ADVOR
Adding the IV drug to loop diuretics in the ADVOR trial improved decongestion success in volume-overloaded patients with acute decompensated heart...
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‘Conservative’ USPSTF primary prevention statin guidance finalized
The new statement invites comparison with the more comprehensive 2018 ACC/AHA-multisociety statin guidelines. A slew of editorials across several...
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‘Obesity paradox’ in AFib challenged as mortality climbs with BMI
Mortality rose with body mass index in patients with new atrial fibrillation in a GARFIELD-AF analysis, which also examined BMI effects on...
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Hot weather risk for nonfatal MI hinted for antiplatelets, beta-blockers
Why taking either drug class would promote nonfatal MIs on high-temperature days, or why it may have appeared that way, isn’t clear, but...
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Gout flares linked to transient jump in MI, stroke risk
Causation is plausible, even suspected, say experts, who urge aggressive CV risk-factor management in gout patients and perhaps more willingness...
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Do ICDs still ‘work’ in primary prevention given today’s recommended HF meds?
They might offer fewer meaningful survival gains in patients on the four pillars of HFrEF med therapy, researchers speculate from their study.
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Cardiologists concerned for patient safety after abortion ruling
Clinicians in many U.S. states are in uncharted territory with the country’s new patchwork of abortion legality, but some specialties may feel the...
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Pig-heart transplant case published with new details, insights
For example, heart injury at autopsy didn’t resemble standard graft rejection in humans or other primates, researchers said, nor did viral...
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Add AFib to noncardiac surgery risk evaluation: New support
Preexisting atrial fibrillation should again be part of pre–noncardiac surgery cardiac risk assessment, argues a new report.
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Cause of death in pig heart recipient: New clues
New details on efforts to identify the mechanism of David Bennett’s death tentatively rule out a few possible suspects that had been at the top of...