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FDA tweaks Impella indications on basis of postapproval study
The updated indication tightens the description of eligible patients on the basis of postapproval study results but in line with premarket-study...
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FDA expands list of Getinge IABP system and component shortages
In a letter to providers, the agency added intra-aortic balloon pump systems to a list of Getinge IABP equipment currently in short supply due to...
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IRONMAN galvanizes case for IV iron repletion in heart failure
The trial missed its primary endpoint, but makes unique contributions; many see it as further evidence that the treatment helps iron-deficient...
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Be aware, mindfulness training can lower systolic BP: MB-BP
“This is exactly what we need: a well-done trial with a control group to show that it actually works,” said one expert, cautioning that it...
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Optimize HF meds rapidly and fully after hospital discharge: STRONG-HF
Outcomes were superior with a high-intensity up-titration strategy compared with usual care, but questions about implementation in practice remain...
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Dietary supplements hyped as LDL cholesterol lowering are a bust: SPORT
The list of supplements without effects on LDL in the placebo-controlled trial include commercial preparations of fish oil, cinnamon, garlic,...
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Avoid routine early ECMO in severe cardiogenic shock: ECMO-CS
Early ECMO in this setting is increasingly common, but it didn’t seem to improve outcomes in the trial, compared with a more conservative approach...
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No survival advantage for either torsemide or furosemide in HF: TRANSFORM-HF
One loop diuretic is the most widely used in heart failure, the other may have advantages in some situations, but there’s been no head-to-head...
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AHA 2022 to recapture in-person vibe but preserve global reach
Planners see the meeting’s Chicago return as a hybrid after 2 years relegated to cyberspace as a chance for first impressions on some just...
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FDA OKs Medtronic lead for left bundle branch pacing
A lead already approved for stimulating the His bundle is now also indicated for LBB pacing, another prominent form of conduction system pacing....
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Trial of early intensive meds at HF discharge halted for benefit: STRONG-HF
Topline results point to significant clinical benefit from a strategy featuring early initiation and rapid uptitration of meds for patients...
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FDA approves self-administered, SubQ furosemide preparation
The preparation of the common loop diuretic is said to provide “intravenous-equivalent” dosing for outpatients with heart failure and volume...
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Dapagliflozin DELIVERs regardless of systolic pressure in HFpEF
The finding may alleviate long-standing concerns that starting modestly diuretic SGLT2 inhibitors in patients with heart failure might present a...
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Salt pills for patients with acute decompensated heart failure?
It may seem counterintuitive, but a new trial testing extra sodium intake in patients receiving high-dose intravenous diuretics for acute HF...
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Add PCSK9 inhibitor to high-intensity statin at primary PCI, proposes sham-controlled EPIC-STEMI
The powerful LDL cholesterol–lowering agents aren’t being used to their fullest potential, but giving them early to STEMI patients along with high...