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Decitabine elicits favorable response in high-risk AML/MDS
Single-agent therapy with decitabine elicited favorable responses in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS...
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Worse outcomes for double-hit lymphomas after ASCT
Patients with double-hit lymphomas and double-expressor lymphomas have inferior outcomes after undergoing autologous stem cell transplantation,...
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HCT survivors experience high rates of late respiratory and infectious complications
Cancer survivors who underwent hematopoietic cell transplantation (HCT) face a greater risk for hospitalizations and mortality, compared with...
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ADT not associated with increased risk of dementia in larger study
Treatment with androgen deprivation therapy (ADT) was not associated with an increased risk of dementia in a large, population-based study,...
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DNA methylation markers prognostic for metastatic breast cancer
A novel panel of DNA methylation markers may aid in predicting survival outcomes in metastatic breast cancer.
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Androgen improved survival in elderly AML patients
Elderly patients with acute myeloid leukemia (AML) generally have a poor prognosis, but maintenance therapy with an androgen, norethandrolone,...
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Oral bacterium linked to poor esophageal cancer survival
Fusobacterium nucleatum
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R-CHOP and intensive R-HDS comparable in DLBCL
Overall response rate and long-term outcomes were comparable whether patients received rituximab combined with high-dose sequential chemotherapy (...
News
Palifosfamide plus doxorubicin does not improve survival in sarcoma
Key clinical point: Palifosfamide combined with doxorubicin did not improve survival in metastatic soft tissue sarcoma. Major finding: The median...
News
‘Meaningful’ antitumor activity with lenalidomide monotherapy in ATL
Key clinical point: Lenalidomide demonstrated clinical activity with acceptable toxicity in recurrent or relapsed ATL. Major finding: The overall...
News
Neoadjuvant therapy improves survival in pancreatic cancer
Key clinical point: Neoadjuvant therapy improves outcomes in pancreatic cancer. Major finding: Neoadjuvant therapy was associated with improved...
News
New interventions improve symptoms of GERD
Patients with chronic gastroesophageal reflux disease (GERD) who have failed long-term proton pump inhibitor (PPI) therapy can benefit from...
News
Treatment failure reduced in Barrett’s esophagus with endoscopic mucosal resection
The use of endoscopic mucosal resection before radiofrequency ablation significantly reduced the risk for treatment failure among patients with...