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Study supports add-on therapy for germline and wildtype BRCA mutations
The findings put to rest the notion that patients with germline BRCA mutations would not benefit from carboplatin treatment because of sensitivity...
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‘New first-line standard of care’ in cervical cancer
“Data from KEYNOTE-826 suggest that pembrolizumab plus platinum-based chemotherapy with or without bevacizumab may be a new first-line standard of...
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Fibrosis progression flies below the radar in subclinical ILD
Patients with connective tissue diseases should be monitored for subclinical interstitial lung disease and fibrosis, experts say.
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Infants breathe better when pregnant moms exercise
Physical activity during pregnancy has been demonstrated to reduce the risk of preterm birth, cesarean birth, and children being born either...
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CAR T-cell therapy drives refractory SLE into remission
B-cell depletion with chimeric antigen receptor T cells induced both serologic and clinical remissions in a patient with treatment-resistant lupus...
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How many years of aromatase inhibitor therapy in breast cancer?
Postmenopausal women with hormone receptor–positive breast cancer may need only 2 years of additional endocrine therapy instead of 5, shows a new...
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Good survival, outcomes with TARE for HCC in practice
Transarterial radioembolization was successfully employed with good safety across 25 centers in eight European countries.
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Testosterone replacement shows CV benefit in hypogonadal men
Among men with hypogonadism who received testosterone replacement every 3 months, cardiovascular parameters were better and there were fewer...
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Fibrosis severity in ALD predicts survival
Having significant or advanced fibrosis puts patients with ALD at high risk of death or decompensation in the short term.
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Protein expression may predict HBV DNA suppression
Protein expression patterns after treatment for HBV infections may help clinicians refine therapy.
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Rapid core antigen HCV tests could expand accessibility
Low-cost rapid diagnostic testing for HCV plus lab RNA confirmation of negatives may improve access to treatment in countries with limited...