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Brexanolone appears effective for severe postpartum depression
Women treated with brexanolone show marked improvement in their HAM-D score within 24 hours of the beginning of their infusion.
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Relatives of NAFLD patients: 12-fold higher risk
Close relative with nonalcoholic fatty liver disease indicates risk.
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Urgent surgery said to deserve separate classification
Urgent surgery – more morbidity, six times the deaths.
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Laparoscopic colectomy cost savings linked to surgeon experience
Laparoscopic surgery is not always the less expensive option.
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Rural patients less likely to have bariatric surgery
Bariatric surgery may be needed by, but not accessible to, rural Medicaid patients.
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Immediate-completion lymph node dissection in metastatic melanoma
Is lymph node dissection a must in patients with melanoma and sentinel node metastases?
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Weight gain in pregnancy: Too much and too little can be harmful
A meta-analysis of more than 1 million pregnancies shows the adverse perinatal outcomes associated with weight gain outside the recommended ranges...
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Cirrhosis linked to increased risk of stroke
Does the risk of extrahepatic hemorrhage conferred by cirrhosis extend to the brain?
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Direct microscopy plus nail clipping identifies onychomycosis
Two different diagnostic tests used together will raise the likelihood of an accurate onychomycosis diagnosis.
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Minocycline may delay conversion to MS
The results of a randomized, double-blind, placebo-controlled trial require confirmation in larger and longer trials.
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Large-scale ERAS program reduces postoperative LOS, complications
Surgical quality improvement project takes implementation science to the next level.
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Framingham: Arterial stiffening not inevitable with aging
Framingham heart study longitudinal finding flies in the face of long-held clinical belief about aging.
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Biologics after methotrexate fails: Huge cost, minimal benefit
Prescribing biologics for RA as a first approach is like throwing money in the trash.
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Statins: No benefit as primary prevention in elderly
Are your older, hypertensive, mildly hypercholesterolemic patients taking statins?
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Imatinib cuts mast cells in severe asthma
In a trial, imatinib decreased airway mast-cell counts and airway hyperresponsiveness in adults with asthma, who were not responding well to...