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Posluma approved for PET imaging in prostate cancer
“The study showed that Posluma PET provided clinically valuable information prior to surgery that would likely result in management changes for...
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FDA approves epcoritamab for r/r DLBCL
Epcoritamab for adults with relapsed/refractory diffuse large B-cell lymphoma has been approved by the FDA.
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FDA OKs stem cell therapy for blood cancer patients to reduce infection risks
Stem cell therapy approved by FDA for blood cancer patients aged 12 and older is aimed at reducing the risk of infections.
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AFib risk with cancer drugs underestimated
Many cancer therapies increase the risk of atrial fibrillation, but this is underreported in clinical trials.
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Erythema extent predicts death in cutaneous GVHD
Study: Extent of skin erythema correlates with deaths from graft-versus-host disease in blood cancer patients after stem cell transplants.
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Nicotinamide does not prevent skin cancer after organ transplant
Nicotinamide (vitamin B3) has been shown to prevent nonmelanoma skin cancers in healthy, immunocompetent people, so physicians routinely prescribe...
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Hemophilia A gene therapy under FDA review
Recently published clinical data showed that a costly new gene therapy for hemophilia A was found largely durable at 2 years.
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Strategy to reduce peritoneal metastases in gastric cancer
Surgery and postoperative chemotherapy are standard of care for advanced gastric cancer, but up to half of patients develop peritoneal metastases...
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Omit radiation in older women with low-risk, ER+ breast cancer
Trial randomly assigns 1,326 women who had undergone a lumpectomy to either whole-breast irradiation or no radiation on a background of tamoxifen...
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Docetaxel as alternative to cisplatin for H&N radiotherapy
“This is the first randomized study demonstrating the benefit of an alternate radiosensitizing agent in cisplatin-ineligible patients.”
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Key factors predict gallbladder cancer on routine cholecystectomy
Identifying predictors allows surgeons to send high-risk individuals for oncologic evaluation beforehand and to prepare for intraoperative frozen...
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‘Valid option’ for partial breast irradiation in breast cancer
Study authors suggest that 30 Gy in five daily fractions is a ‘valid option’ for patients who received lumpectomy for early breast cancer.
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FDA OKs sacituzumab govitecan for HR+ metastatic breast cancer
Label expansion for the Trop-2–directed antibody-drug conjugate was based on the TROPICS-02 trial.
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FDA OKs elacestrant for ESR1+ advanced, metastatic breast cancer
The agency also approved the Guardant360 CDx assay as a companion diagnostic to identify breast cancer patients who meet the treatment...
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Tucatinib plus trastuzumab approved for HER2+ colorectal cancer
This is the first FDA-approved treatment for HER2-positive metastatic colorectal cancer.