News
FDA approves quizartinib for newly diagnosed AML
- Author:
- M. Alexander Otto, PA, MMS
Cardiac risks mean the targeted tyrosine kinase inhibitor is available only through a Risk Evaluation and Mitigation Strategies program.
News
Radiation approach improves swallowing in head, neck cancer
- Author:
- M. Alexander Otto, PA, MMS
“DO-IMRT should be considered a new standard of care.”
News
Lower-dose FOLFIRINOX effective, safer for pancreatic cancer
- Author:
- M. Alexander Otto, PA, MMS
“The best dose modification protocol” remains to be determined and standardized for metastatic pancreatic cancer.
News
Was the fruquintinib trial for metastatic CRC a win?
- Author:
- M. Alexander Otto, PA, MMS
“One could debate if 2.6 months of more time is worth the medication getting regulatory approval, or debate pricing when it’s approved, or delve...
News
No benefit to adding limited radiation in advanced cancer
- Author:
- M. Alexander Otto, PA, MMS
Median overall survival was not significantly better with radiotherapy, compared with the control group, nor was the objective response rate.
News
Diabetes may short circuit pembrolizumab benefits in NSCLC
- Author:
- M. Alexander Otto, PA, MMS
"There is an urgent need to validate our findings and explore whether outcomes in these patients can be improved by better glycemic control."
News
FDA approves first gene therapy for hemophilia A
- Author:
- M. Alexander Otto, PA, MMS
The expensive, one-time, single-dose IV infusion for severe hemophilia A may offer patients years of freedom from infusions.
News
MRI identifies rectal cancer patients who can skip CRT
- Author:
- M. Alexander Otto, PA, MMS
Study suggests that neoadjuvant chemoradiation therapy can be restricted to patients at high risk of locoregional recurrence.
News
Breast cancer family history linked to better BC survival
- Author:
- M. Alexander Otto, PA, MMS
A family history of breast cancer was associated with a lower risk of breast cancer-specific death, after adjustments, a new study finds.
News
No safe dose of cardiac radiation in children?
- Author:
- M. Alexander Otto, PA, MMS
“These findings solidify the need to consider cardiac substructure doses in [pediatric] radiation treatment planning and in survivorship care.”
News
‘New standard of care’ for capecitabine hand-foot syndrome
- Author:
- M. Alexander Otto, PA, MMS
“For me as a GI oncologist, topical diclofenac for prevention of HFS for patients on capecitabine is practice changing,” ...
News
Risk of falls seen with newer antiandrogens for prostate cancer
- Author:
- M. Alexander Otto, PA, MMS
The take-home message is that the findings give men – and the physicians who counsel them – a fuller idea of what to expect when considering using...
News
Safe to stop immunotherapy at 2 years in stable lung cancer
- Author:
- M. Alexander Otto, PA, MMS
“These data may provide reassurance to us and patients that discontinuing treatment at 2 years can confer the same overall survival as extended...
News
Oncologist pleads guilty to prescription drug fraud
- Author:
- M. Alexander Otto, PA, MMS
Dr. Kachadourian was paid more than $170,000 for purchasing and allowing others to purchase in her name millions of dollars in prescription drugs...
News
Warning on use of sotorasib after ICI in lung cancer
- Author:
- M. Alexander Otto, PA, MMS
“We suggest avoiding starting sotorasib within 30 days from the last anti–PD-(L)1 infusion.”