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Statin may reduce vaso-occlusive pain in SCD
Photo courtesy of the CDC ORLANDO, FL—In a small study, the cholesterol-lowering medication simvastatin reduced the frequency of vaso-occlusive...
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Graft source and timing of HSCT affect survival in SCD
Photo by Chad McNeeley ORLANDO, FL—In a large, registry-based study, transplants from human leukocyte antigen (HLA)-identical sibling donors...
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CAR T-cell therapy dubbed ‘promising’ for MM
Photo courtesy of ASH ORLANDO, FL—Chimeric antigen receptor (CAR) T cells can have “powerful activity” in patients with multiple myeloma (MM),...
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HU noninferior to transfusion for stroke prevention in SCD
Photo courtesy of ASH ORLANDO, FL—Hydroxyurea (HU) is noninferior to chronic blood transfusions for reducing the risk of stroke in children with...
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Combination offers ‘important new option’ for CLL, team says
Photo courtesy of ASH ORLANDO, FL—Idelalisib, the first-in-class PI3Kδ inhibitor, combined with bendamustine and rituximab (BR) for relapsed/...
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Triplet disappoints in follicular lymphoma trial
Photo courtesy of ASH ORLANDO, FL—A 3-drug regimen is likely not worth pursuing as a first-line treatment option for follicular lymphoma (FL),...
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Source of FVIII replacement matters, study shows
Photo courtesy of ASH ORLANDO, FL—The source of factor VIII (FVIII) replacement therapy affects the risk of inhibitor development in previously...
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mAb could provide targeted approach to HLH treatment
ASH Annual Meeting Photo courtesy of ASH ORLANDO, FL—A monoclonal antibody (mAb) targeting interferon-gamma (IFNγ) has shown promise for treating...
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CAR exhibits activity in resistant B-cell malignancies
Photo courtesy of ASH ORLANDO, FL—Allogeneic chimeric antigen receptor (CAR) T cells directed against CD19 can have “significant” activity...
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Ibrutinib ‘treatment of choice’ in rel/ref MCL
Annual Meeting Photo courtesy of ASH ORLANDO, FL—The BTK inhibitor ibrutinib should be considered the treatment of choice for patients with...
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Timing of irradiation affects RCCs
ANAHEIM, CA—The timing of gamma irradiation influences in vitro characteristics of red cell concentrates (RCCs), according to a new study. The...
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Newer apheresis system appears superior to standard
Photo by ec-jpr ANAHEIM, CA—A newer, more streamlined apheresis system yields more CD34+ cells from stem cell transplant donors than a previous...
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Survey: 3 in 10 MSMs don’t comply with UK blood donor policy
Photo by Marja Helander ANAHEIM—A survey of UK blood donors suggests that as many as 30% of donors who are men who have sex with men (MSM) may...
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Interventions can treat, prevent iron deficiency in blood donors
ANAHEIM, CA—Data from the STRIDE study have revealed interventions that can mitigate iron deficiency in repeat blood donors. The study showed...
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Assay can detect and classify DOACs
Photo by Juan D.