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Group identifies ‘essential’ genes in AML
CRISPR-based genetic screens have revealed essential genes—those required for cellular proliferation and survival—in 14 acute myeloid leukemia (...
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Why like attracts like in malaria
Past research has shown that malaria-carrying mosquitoes prefer to feed on humans who are already infected with malaria. Now, researchers...
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Computer predicts remission, relapse in AML
Researchers say they have developed the first computer machine-learning model to accurately predict which patients diagnosed with acute myeloid...
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Genetic profiling can guide HSCT in MDS, team says
Genetic profiling can be used to determine which patients with myelodysplastic syndrome (MDS) are likely to benefit from allogeneic hematopoietic...
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Study shows no increased risk of mutations with iPSCs
The use of induced pluripotent stem cells (iPSCs) in biomedical research and medicine has been slowed by concerns that these cells are prone to...
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Algorithm predicts NRM, GVHD after HSCT
A biomarker algorithm can identify patients with a high risk of graft-vs-host disease (GVHD) and non-relapse mortality (NRM) after hematopoietic...
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iPSCs used to identify potential treatment for DBA
Researchers have used induced pluripotent stem cells (iPSCs) to identify a compound that could treat Diamond Blackfan anemia (DBA).
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Resistant malaria parasite spreading through Asia
A lineage of multidrug-resistant malaria parasite has spread widely and is now established in parts of Thailand, Laos, and Cambodia, according to...
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FDA approves IVIG product for PI and chronic ITP
The US Food and Drug Administration (FDA) has approved an intravenous immunoglobulin (IVIG) product (Gammaplex® 10%) for the treatment of primary...
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Investigators report new risk loci for CLL
Investigators say they have identified 9 new risk loci for chronic lymphocytic leukemia (CLL). The team says the research, published in Nature...
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Sickle cell trait may confound blood sugar readings
A new study suggests that hemoglobin A1c (HbA1c), a biomarker used to measure blood sugar over time, may not perform as accurately among African-...
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‘Alternative’ BMT deemed ‘promising’ for SAA
Researchers have reported a “promising” treatment approach for refractory, severe aplastic anemia (SAA). The regimen consists of...
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US-trained docs have higher patient death rate
A large study has revealed a lower death rate among US patients treated by internationally trained doctors rather than US-trained doctors.
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Obinutuzumab approved to treat FL in Canada
Health Canada has approved the use of obinutuzumab (Gazyva®), an anti-CD20 monoclonal antibody, in patients with follicular lymphoma (FL).
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NCCN releases patient guidelines for WM/LPL
The National Comprehensive Cancer Network® (NCCN) has published a set of guidelines for patients with Waldenström’s macroglobulinemia/...