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Method identifies effective treatments for leukemias, lymphomas
An ex vivo drug screening method can reveal optimal therapies for patients with hematologic malignancies, according to research published in The...
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PTSD can persist in cancer survivors
Cancer patients may experience lasting post-traumatic stress disorder (PTSD), according to a study published in the journal Cancer. Approximately...
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Withdrawn drug receives orphan designation for HA
The US Food and Drug Administration (FDA) has granted orphan drug designation to rofecoxib (TRM-201) as a potential treatment for degenerative...
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Nilotinib approved to treat kids with CML in EU
The European Commission has approved nilotinib (Tasigna®) for the treatment of pediatric patients. The drug is now approved to treat children age...
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CD22-CAR therapy shows activity in rel/ref B-ALL
Researchers say they have reported the first results demonstrating clinical activity of a CD22-directed chimeric antigen receptor (CAR) T-cell...
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NOACs may do less harm to kidneys than warfarin
New research suggests warfarin may produce worse renal outcomes than non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial...
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Technique may predict treatment outcomes in MM
A cell-measuring technique can help predict how multiple myeloma (MM) patients will respond to different therapies, according to research...
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Antimalarial might fight Zika virus
Preclinical research suggests a drug used to prevent and treat malaria may also be effective against Zika virus. Investigators found that...
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Team discovers mechanism of resistance in AML
Researchers say they have uncovered a target to overcome drug resistance in acute myeloid leukemia (AML). The team discovered how a linkage...
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Product approved to treat patients with hemophilia A and inhibitors
The US Food and Drug Administration (FDA) has approved use of emicizumab-kxwh (Hemlibra®), a bispecific factor IXa- and factor X-directed antibody...
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FDA expands approval of obinutuzumab
The US Food and Drug Administration (FDA) has expanded the approved use of obinutuzumab (Gazyva®). The drug is now approved for use in...
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CAR T-cell therapy on fast track with FDA, EMA
A chimeric antigen receptor (CAR) T-cell therapy, bb2121, has received breakthrough therapy designation from the US Food and Drug Administration (...
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Rigosertib produces better OS in MDS than tAML
Rigosertib has demonstrated activity and tolerability in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia transformed from...
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Drug can treat severely ill SCD patients, case suggests
ATLANTA—Results of a case study suggest voxelotor (previously GBT440) can be effective in severely ill patients with sickle cell disease (SCD)....
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FDA approves generic clofarabine
The US Food and Drug Administration (FDA) has approved Dr.