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AVP stimulates red blood cell production
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- HT Staff
Researchers say they have uncovered a new function of arginine vasopressin (AVP). It seems this hormone does more than maintain fluid balance for...
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Team finds no evidence that gadolinium causes neurologic harm
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CHICAGO—There is no evidence to suggest that accumulation of gadolinium in the brain speeds cognitive decline, according to research presented at...
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Study reveals potential target for AML treatment
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New research has revealed a potential therapeutic target for acute myeloid leukemia (AML)—the methyl transferase enzyme METTL3. Researchers found...
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Inhibitor exhibits activity against range of lymphomas
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Preclinical research suggests the dual PI3K/mTOR inhibitor PQR309 has activity against several types of lymphoma and works well in combination...
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FDA grants drug orphan designation for AML, MDS
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- HT Staff
The US Food and Drug Administration (FDA) has granted orphan drug designation to AMV564, a CD33/CD3 bispecific antibody, for the treatment of...
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Group develops MM-specific CAR T-cell therapy
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Researchers say they have identified a multiple myeloma (MM)-specific target for chimeric antigen receptor (CAR) T-cell therapy. The team...
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Mogamulizumab BLA receives priority review
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The US Food and Drug Administration (FDA) has accepted for priority review the biologics license application (BLA) for mogamulizumab....
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FDA grants priority review to NDA for avatrombopag
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- HT Staff
The US Food and Drug Administration (FDA) has granted priority review to the new drug application (NDA) for avatrombopag. Avatrombopag is a...
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Study reveals predictor of early mortality in AML
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New research has shown an increased risk of early death in patients with acute myeloid leukemia (AML) who have high levels of indoleamine 2,3...
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Thoughts, emotions linked to opioid use in SCD
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Results of a small study suggest that negative thoughts and emotions may increase opioid use in patients with sickle cell disease (SCD)....
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Authors’ contributions to studies often unclear
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Although many scientific journals try to provide details about authors’ contributions to a publication by requiring explicit statements,...
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Team identifies genetic differences between MM patients
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Researchers say they have identified significant genetic differences between African-American patients with multiple myeloma (MM) and Caucasian...
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How CLL patients weigh treatment efficacy, safety, and cost
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New research suggests patients with chronic lymphocytic leukemia (CLL) are willing to trade treatment efficacy for a reduced risk of side effects...
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Review suggests low incidence of BIA-ALCL in Canada
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Results of a safety review suggest there is a low incidence of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) in Canada....
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CCSs have increased risk of hypertension
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- HT Staff
A study of childhood cancer survivors (CCSs) suggests these individuals have an increased risk of developing hypertension as adults. The CCSs...