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Neutrophils cause hemorrhage in thrombocytopenia
Image by Volker Brinkmann Researchers have found that hemorrhage occurs in the context of thrombocytopenia when neutrophils cross the endothelial...
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Prolonged sitting may increase cancer risk in women
Photo by Petr Kratochvil Results of a large study indicate that women who spend their leisure time sitting for prolonged periods—6 or more hours...
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YA cancer survivors hospitalized more often
Photo courtesy of St.
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NICE recommends edoxaban for VTE
Image by Keven MacKenzie The UK’s National Institute for Health and Care Excellence (NICE) has issued a draft guidance recommending the oral...
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Prenatal test results linked to cancer in mothers
Photo by Nina Matthews Researchers have again found evidence to suggest that tests used to identify chromosomal fetal disorders can detect occult...
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JAK2 inhibitor could treat B-ALL
Photo courtesy of the Dana-Farber Cancer Institute A type II JAK2 inhibitor has shown activity against B-cell acute lymphoblastic leukemia (B-ALL...
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Restrictive transfusion may be safe for AUGIB
Photo by Elise Amendola Results of a pilot study suggest a restrictive transfusion strategy may be safe for patients with acute upper...
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ASCO updates guideline on CSFs
The American Society of Clinical Oncology (ASCO) has updated its clinical practice guideline on hematopoietic colony-stimulating factors (CSFs)....
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Length of cell-cycle phase affects HSC function
in the bone marrow Shortening the G1 phase of the cell cycle can improve the production and function of hematopoietic stem cells (HSCs),...
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Drug worth pursuing as T-ALL therapy, researchers say
Photo courtesy of Children’s Cancer Institute A drug that previously fell short of expectations holds promise for treating T-cell acute...
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Adopting may be more difficult for cancer survivors
by Vera Kratochvil Cancer survivors may face more challenges when trying to adopt a child than individuals without a history of cancer, according...
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Gene regulates HSPC frequency, function
Photo by Aaron Logan A genome-wide association study conducted in mice has provided new insights regarding hematopoietic stem/progenitor cells (...
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Ibrutinib approved to treat WM in EU
The European Commission has granted marketing authorization for ibrutinib (Imbruvica) to treat Waldenstrom’s macroglobulinemia (WM). The Bruton’s...
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Transcription factor promotes MM progression
rim of a bone spicule (pink) New research indicates that multiple myeloma (MM) cells can “disguise” themselves as bone cells to elude the immune...
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Older cancer patients under-utilize advanced care planning
Photo courtesy of NCI and Mathews Media Group Survey results suggest the use of aggressive treatment at the end of life is on the rise among...