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Reporting requirements may affect trial outcomes
Photo by Esther Dyson The reporting requirements developed to increase transparency in US medical research may lead to fewer positive trial...
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FDA grants drug orphan designation for ITP
Photo by Linda Bartlett The US Food and Drug Administration (FDA) has granted orphan designation to veltuzumab for the treatment of immune...
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Nanocapsules exploit biology to destroy blood clots
Image by Andre E.X.
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Drug gets orphan designation for CTCL
The European Commission has granted orphan drug designation to synthetic hypericin, the active pharmaceutical ingredient in SGX301, for the...
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Physical activity can benefit kids with cancer
Photo by Bill Branson Children with cancer can benefit from “adapted” physical activities, according to a pilot study published in...
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DAPT may be better for older patients after PCI
Photo courtesy of the CDC A new study suggests less is more when it comes to antithrombotic therapy for higher-risk older patients with atrial...
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Recombinant vWF can safely halt bleeding in vWD
Results of a phase 3 trial suggest the recombinant von Willebrand factor (rvWF) product BAX 111 can safely control bleeding in patients with...
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T-cell activation is a dynamic process, study shows
plasma membrane upon T-cell activation.
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Group creates vascular graft that resists thrombosis
The enlarged section shows the drug-loaded film that coats the inside of the graft. Image courtesy of ITMO University/Yulia Chapurina Researchers...
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FDA clears 7-day storage of platelets
The US Food and Drug Administration (FDA) has cleared a label change for the Fenwal Amicus system, a cell-separation device, to allow for 7-day...
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How a molecule turns B cells into macrophages
pseudopodia to engulf particles The transcription factor C/EBPα reprograms B cells into macrophages by “short-circuiting” the cells so they re-...
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Microfluidics can improve epigenomic analysis, team says
his student, Zhenning Cao. Dr Lu is holding the chip used in the study. Photo from Virginia Tech A new technique enables epigenomic analysis...
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Newfound mechanism could be used to fight cancers
apoptosis in cancer cells Researchers say they have identified a new mechanism by which the tumor suppressor protein p53 triggers apoptosis, and...
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Delayed cancer diagnosis tied to care dissatisfaction
Photo courtesy of NIH Patients who make 3 or more trips to the general practitioner (GP) before they are referred for cancer tests are more...
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Combo may overcome TKI resistance in CML
Schürch, MD, PhD, (left) and Adrian Ochsenbein, MD Photo by Susi Bürki Combining a tyrosine kinase inhibitor (TKI) with a monoclonal antibody (...