Erik Greb joined the staff of Neurology Reviews in January 2012. Since then, he has attended scientific conferences, conducted video interviews, and written about clinical research in multiple sclerosis, epilepsy, Parkinson's disease, Alzheimer's disease, stroke, and other neurologic disorders. In addition to news articles, Erik has written investigative stories about multiple sclerosis, headache, and epilepsy. He previously wrote about pharmaceutical manufacturing, drug formulation and delivery, quality assurance, and regulation for Pharmaceutical Technology.
News
Consensus document reviews determination of brain death
The recommendations are the minimum criteria for the determination of brain death or death by neurologic criteria.
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Cardiovascular risk factors tied to midlife cognitive decline
Hypertension, diabetes, and smoking can affect cognition at an age much younger than previously believed.
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Less REM sleep tied to higher mortality
Less REM sleep is associated with an increased risk for death in middle-aged and older adults.
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Can DBS in early Parkinson’s disease reduce disease progression?
Compared with standard treatment, DBS plus drug therapy appears to reduce the need for polypharmacy.
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Migraine is often a deciding factor in pregnancy planning
Among women with migraine, those who were younger, had menstrual migraine, or had chronic migraine were more likely to decide to not become...
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Consistent effects for galcanezumab in cluster headache
Most patients whose PGI-I score improved in one cluster bout also improved in a subsequent bout.
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Headache may predict clinical evolution of COVID-19
Headache onset could occur during the presymptomatic or symptomatic phase of COVID-19 and could resemble tension-type or migraine headache.
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Few patients with migraine clear barriers to optimal care
Less than 8% of patients with episodic migraine and less than 2% of patients with chronic migraine were able to overcome four key treatment...
News
Function in MS may vary significantly within EDSS scores
Mean normalized velocity of preferred walking speed may vary by more than 20% within EDSS groups and overlap by more than 20% between groups.
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Telerehabilitation may be effective in MS
Patients with MS may achieve equivalent benefits and increased cost savings with telerehabilitation, compared with outpatient rehabilitation.
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Nilotinib is safe in moderate and advanced Parkinson’s disease
Although the drug is safe and tolerable, it penetrates the brain poorly and does not change levels of dopamine or its metabolites.
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Chronic migraine is associated with changes in the amygdala
Changes in the volume and connectivity of the amygdala are associated with headache frequency and affective states.
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AAN publishes ethical guidance on patient care during the pandemic
The guidance reviews adaptations to inpatient and outpatient care and indicates the need for protocols to allocate scarce medical resources.
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New research confirms the efficacy and safety of onasemnogene abeparvovec for SMA
Three investigations indicate that the treatment allows children, including those who are presymptomatic, to achieve and maintain motor milestones...