News
Pushing LDL below 25 mg/dL with alirocumab safe ‘so far’
Key clinical point: LDL cholesterol levels below 25 mg/dL induced by a superpotent investigational lipid-lowering agent appear to be safe through...
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Adapalene/benzoyl peroxide + doxycycline outscores oral isotretinoin
Key clinical point: The combination of fixed-dose adapalene/benzoyl peroxide plus oral doxycyline is an alternative to oral isotretinoin in...
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Simple risk score predicts dementia risk in type 2 diabetes
Key clinical point: It’s now readily possible to predict the 10-year dementia risk for individuals with type 2 diabetes.
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Psoriasis: Brodalumab maintains efficacy through 144 weeks
Key clinical point: The investigational interleukin-17 receptor A inhibitor brodalumab maintained strong clinical efficacy throughout 144 weeks of...
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Dupilumab advances for severe atopic dermatitis
Key clinical point: A promising new therapy with a novel mechanism of action is progressing through the pipeline for adults with refractory atopic...
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Dupilumab Advances for Severe Atopic Dermatitis
Key clinical point: A promising new therapy with a novel mechanism of action is progressing through the pipeline for adults with refractory atopic...
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IMPROVE-IT: Ezetimibe/simvastatin further reduces cardiovascular events
Key clinical point: Combined therapy with ezetimibe and simvastatin reduces cardiovascular events more than simvastatin alone in high-risk...
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Increased Alzheimer’s risk with long-term benzodiazepine use
Key clinical point: Chronic use of benzodiazepines by the elderly may boost their risk of Alzheimer’s disease in a dose-dependent fashion.
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Less daytime sleepiness with lurasidone for schizophrenia
Key clinical point: Patients with an acute exacerbation of schizophrenia treated with lurasidone experience less sleepiness during waking hours,...
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Certolizumab achieves sustained skin improvement in psoriatic arthritis
Key clinical point: Certolizumab pegol maintains sustained improvement in the dermatologic manifestations of psoriatic arthritis through 96 weeks...
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Telephone CPR training boosts cardiac arrest survival
Key clinical point: Adoption of the most recent AHA guidelines on telephone CPR by EMS dispatchers will lead to vast improvement in survival for...
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Switch to long-acting antipsychotics improved treatment attitude
Key clinical point: A switch to a long-acting injectable antipsychotic proved beneficial in multiple ways in patients with schizoaffective...
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Injectable paliperidone palmitate reduces incarcerations in schizophrenia
Key clinical point: Real world schizophrenia patients with a history of incarceration are less likely to return to jail if they’re on long-acting...
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Low-risk actinic keratosis? No such thing
Key clinical point: Actinic keratoses traditionally considered low-risk AK 1s with dysplasia confined to the basal one-third of the epidermis can...