News
SOFT trial endorses selective ovarian suppression in early breast cancer
Key clinical point: Ovarian function suppression plus adjuvant exemestane is the best therapy for women with hormone receptor–positive early...
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Pembrolizumab shows efficacy in advanced triple-negative breast cancer patients
Key clinical point: Immunotherapy with pembrolizumab benefits a subset of patients with advanced, heavily pretreated triple-negative breast cancer...
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Implications of cholesterol guidelines for cardiology practices
Key clinical point: As U.S. cardiologists increasingly “get with the guidelines” regarding cholesterol lowering, expect to see large increases in...
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Oral tofacitinib scores against psoriasis in phase III trial
Key clinical point: Multiple measures of quality of life and disease burden improved similarly in psoriasis patients regardless of whether they...
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Psoriasis Is Independently Associated With Advanced Liver Fibrosis
Key clinical point: Noninvasive screening for advanced hepatic fibrosis may be in order for older patients with mild psoriasis never treated...
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Psoriasis is independently associated with advanced liver fibrosis
Key clinical point: Noninvasive screening for advanced hepatic fibrosis may be in order for older patients with mild psoriasis never treated...
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Novel oral prophylaxis tames hereditary angioedema
Key clinical point: A safe and effective oral daily drug for reducing the frequency of hereditary angioedema attacks is in the works.
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Surprising new findings on hypertension in elderly blacks
Key clinical point: Older black patients with hypertension are less likely, by an absolute 10%-15%, to be at goal blood pressure than are their...
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TOPCAT reconsidered: Say ‘nyet’ to Russian data
Key clinical point: Prescribing spironolactone for patients with symptomatic heart failure with preserved ejection fraction may reduce their risks...
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Heart failure device shown safe in PARACHUTE III
Key clinical point: A percutaneous device known as the Parachute, when placed in the apex of the left ventricle, may slow or reverse progression...
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New evidence suggests 2014 hypertension guidelines could backfire
Key clinical point: Adoption of the less aggressive blood pressure goal of 150/90 mm Hg for patients age 60 and older as recommended in the 2014...