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Avelumab active in recurrent or refractory ovarian cancer
Another cancer immunotherapy agent has positive results in ovarian cancer, which supports ongoing investigations of this checkpoint inhibitor in...
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Four distinct IgG4-related disease groups described in study
This large, international, multicenter cohort study used a novel cluster analysis method.
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Matched transplant improves stroke risk indicator in sickle cell anemia
Matched sibling donor hematopoietic stem cell transplants reduced an indicator of stroke risk, suggesting that the intervention may improve...
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Renal transplant improves survival in lupus nephritis patients
Transplant conferred a 70% reduction in overall death risk in patients with end-stage renal disease due to lupus nephritis.
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Autologous transplant linked to PFS benefit in MCL
No overall survival benefit was detected in this retrospective study, in contrast to a previous analysis.
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Medicaid youth suicides include more females, younger kids, hanging deaths
Findings captured in Medicaid claims could help identify periods known to be tied to heightened suicide risk, such as right after discharge from...
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Obinutuzumab-based regimens yield durable remissions in CLL
The findings suggest these new combinations may be more effective at clearing residual disease than rituximab-based therapy.
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Online tools support hemophilia A prophylaxis changes
Individualized pharmacokinetic profiles developed using the web-based tools may have been a factor in improved adherence and bleeding rates.
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HDL-P subfractions may be prognostic in heart failure
Study may spur investigations into HDL particles.
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Lung screening complications costly, more prevalent than in trial setting
Patients and physicians should be discussing the potential harms and downstream costs in shared decision-making visits.
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New hypopnea criteria ID unique OSA patient subset
The revised OSA threshold pointed to a increased risk for arrhythmias in the patients.
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Neoadjuvant degarelix more effective than triptorelin for ovarian suppression
Degarelix, a gonadotropin-releasing hormone (GnRH) antagonist approved for prostate cancer, was more effective than the GnRH agonist triptorelin...
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Puppy bite at yoga retreat leads to rabies death: Prompts health warning
Individuals going to rabies-endemic countries need a pretravel consultation with a travel health specialist regarding preexposure prophylaxis.
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Actionable mutations more likely in women with both breast and uterine cancer
At least one actionable mutation was seen in 14% of women with breast and uterine cancer, compared with 9.3% of women with breast cancer only, in...
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Poor-prognosis cancers linked to highest suicide risk in first year
Pancreatic and lung cancer patients had high rates of suicide in comparison to the general population, while breast and prostate cancer patients...