News
Dupilumab may reduce dysphagia in adults with eosinophilic esophagitis
Results of phase 2 study show improvements in histologic, endoscopic, and patient-reported dysphagia outcome measures.
News
In older patients with immune-mediated TTP, atypical features may delay diagnosis
Thrombocytopenia with anemia should alert physicians to this possible rare diagnosis in older patients with nonspecific neurological abnormalities...
News
Treatment guided by remote readings works when used as intended
PHILADELPHIA –
Article
Cardiotoxicity after checkpoint inhibitor treatment seen early, linked to elevated biomarkers
PHILADELPHIA – The findings support monitoring of cardiac biomarkers in the initial phase of checkpoint inhibitor treatment to identify patients...
News
Machine learning–derived risk score predicts heart failure risk in diabetes patients
Highest WATCH-DM scores linked to 5-year heart failure risk approaching 20%.
News
Milrinone beats dobutamine in extending survival in HF
PHILADELPHIA – Survival benefit favored milrinone regardless of indication for use in continuous outpatient intravenous inotropic therapy.
News
Clinical trial enrollment linked to lower death rate in lung cancer patients
ALEXANDRIA, VA. – Access to promising agents, enhanced supportive care, or both could provide direct patient benefit.
News
Out-of-pocket cost of oral TKIs linked to poor lung cancer survival
ALEXANDRIA, VA. – If confirmed in a nationally representative study, findings could have implications for health policy and oncology practice.
News
Pyrotinib bests lapatinib in HER2+ metastatic breast cancer treatment
The pan-ErbB inhibitor pyrotinib plus capecitabine had manageable toxicity, a significantly higher ORR, and significantly longer PFS, compared...
News
HIV drug may enhance efficacy of chemoradiation in locally advanced lung cancer
Strategy incorporating protease inhibitor nelfinavir yields promising efficacy, acceptable toxicity in locally advanced non–small cell lung cancer...
News
PCSK9 inhibition cuts events in very-high-risk groups
ODYSSEY OUTCOMES analyses peg prior CABG and polyvascular disease as targets for alirocumab.
News
Pretreatment CT data may help predict immunotherapy benefit in ovarian cancer
Fewer sites of disease and lower intratumor heterogeneity on contrast-enhanced CT may indicate a higher likelihood of durable response to immune...
News
Recurrence score may help predict chemotherapy benefit in grade 3 breast cancers
In data that complement the TAILORx findings, chemotherapy was not linked with significantly improved OS for those with a low recurrence score...
News
USPSTF expands BRCA1/2 testing recommendations
Personal cancer history, ancestry now key factors in decision to assess, counsel, and test for potentially harmful mutations in BRCA1/2 genes.
News
Post-TAVR anticoagulation alone fails to cut stroke risk in AFib
By contrast, antiplatelet therapy linked to reduced risk of stroke, whether or not oral anticoagulation was used in this PARTNER II substudy.