News
Worry may attenuate link between psychiatric symptoms, poorer cognitive performance
Key clinical point: In older adults, worry seems to attenuate the relationship between anxiety and depression and poorer cognitive performance....
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Cortical thinning may not be tied to executive dysfunction in late-life depression
Key clinical point: Cortical thinning may not be the major reason for executive dysfunction among patients with late-life depression. Major...
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Fluticasone furoate/vilanterol edged out usual COPD care in real-world trial
Key clinical point: A once-daily inhaled combination of fluticasone furoate and vilanterol was associated with statistically fewer COPD...
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Study supports extending docetaxel therapy in metastatic castration-resistant prostate cancer
Key clinical point: The number of docetaxel cycles independently predicted overall survival in metastatic castration-resistant prostate cancer (...
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Large retrospective study challenges updated ASCO-CAP HER2 categorizations
Key clinical point: Clinical trial data support the original ASCO-CAP categories for HER2 status, not the updated categories from the most recent...
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Mucosal healing linked to long-term clinical benefits in ulcerative colitis
Mucosal healing in ulcerative colitis significantly improves the chances of long-term clinical remission without the need for corticosteroids or...
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Real-world study: 8 weeks of two-drug combo highly effective against HCV
Regimen led to sustained viral response (SVR) in 94% of noncirrhotic, treatment-naive, genotype 1 hepatitis C virus–infected patients, based on a...
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Study reinforced value of preconception IBD care
Key clinical point: Preconception care with intensive follow-up seems to help prevent relapse of IBD during pregnancy. Major finding: Women who...
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Fecal immunochemical testing, colonoscopy outperformed multitarget stool DNA testing
Fecal immunochemical testing and colonoscopy detected colorectal cancer (CRC) more effectively and cheaply than did multitarget stool DNA testing...
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Andexanet controlled factor Xa inhibitor–related bleeding
Key clinical point: Andexanet alfa achieved effective hemostasis in most patients with acute major bleeding on factor Xa inhibitors. Major finding...
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Survival in CLL predicted by minimum residual disease
Key clinical point: Quantifying minimum residual disease significantly improved the accuracy of progression-free survival estimates in patients...
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Extramedullary disease did not independently predict AML survival
Key clinical point: Extramedullary disease does not appear to independently predict overall survival in patients with newly diagnosed acute...
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CPAP fell short for preventing cardiovascular events
Key clinical point: About 3.3.
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Clinical decision tree pinpointed risk of extended-spectrum beta-lactamase bacteremia
Key clinical point: A clinical decision tree helped identify bacteria producing extended-spectrum beta-lactamases. Major finding: The positive...