News
Vitiligo linked to moles, tanning ability, blistering sunburn
- Author:
- Amy Karon
An analysis of data from the Nurses’ Health Study provides some new information on vitiligo risk factors in white women.
News
Low-volume PEG linked to hypokalemia in at-risk patients
- Author:
- Amy Karon
Baseline potassium testing and supplementation may mitigate risk.
News

Methotrexate prolonged efficacy of steroid injections in oligoarticular JIA
- Author:
- Amy Karon
The combination of intra-articular corticosteroids and methotrexate could take center stage in treat-to-target strategies for children with...
News
In CLL, specific mutation is key to ibrutinib resistance
- Author:
- Amy Karon
Specific mutations precede relapse in ibrutinib-treated CLL, offering an opportunity to target asymptomatic clonal expression with novel therapies...
News

Guideline: Prioritize nondrug therapies for low back pain
- Author:
- Amy Karon
Prioritize nonpharmacologic therapies for low back pain of any duration, according to an updated guideline from the American College of Physicians...
News

Eradicate HCV in patients with HIV, regardless of fibrosis stage
- Author:
- Amy Karon
Eradicating hepatitis C virus in HIV-coinfected patients was associated with a significantly lower risk of diabetes mellitus and possibly chronic...
News
Worse outcomes with video laryngoscopy in ICU
- Author:
- Amy Karon
Video laryngoscopy, at least in the ICU, is no better than direct laryngoscopy, and in fact carries higher risks of life-threatening events.
News
Ibrutinib, palbociclib yield durable complete responses in pretreated mantle cell lymphoma
- Author:
- Amy Karon
SAN DIEGO – A “mechanism-based” combination of ibrutinib and palbociclib was reasonably well tolerated and induced complete responses in 44% of...
News

Early mild cognitive impairment in Parkinson’s leads to dementia in more than 40%
- Author:
- Amy Karon
Developing persistent mild cognitive impairment soon after being diagnosed with Parkinson’s disease significantly increased the risk of subsequent...
News
Bortezomib-based regimen led to durable remissions in mantle cell lymphoma
- Author:
- Amy Karon
First-line therapy with bortezomib plus modified hyper-CVAD followed by rituximab maintenance induced durable remissions in mantle cell lymphoma...
Article

Study supports multigene germline testing in colorectal cancer
- Author:
- Amy Karon
About 10% of patients with colorectal cancer had at least one germline mutation known to increase the risk of cancer, according to results from a...
News
AGA Clinical Practice Update: Clostridium difficile in IBD
- Author:
- Amy Karon
Inflammatory bowel disease increases the risk and severity of <i>Clostridium difficile</i> infection while the infection tends to...
News

AGA Guideline: Acute liver failure
- Author:
- Amy Karon
Physicians should avoid routinely testing patients with acute liver failure for Wilson’s disease unless there is “high clinical suspicion” for the...
News
BOS beat placebo for eosinophilic esophagitis
- Author:
- Amy Karon
Budesonide oral suspension was safe and significantly outperformed placebo on validated measures of eosinophilic esophagitis, according to a first...
Video

VIDEO: Sofosbuvir with velpatasvir beat other HCV GT3 regimens
- Author:
- Amy Karon
Regimens containing sofosbuvir and velpatasvir were most effective for treating both cirrhotic and noncirrhotic genotype 3 hepatitis C virus...