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Diabetes management: Beyond hemoglobin A1c
Other factors include cardiovascular benefit, weight control, hypoglycemia risk, and cost.
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In reply: Metformin for type 2 diabetes
The American Diabetes Association recommends periodic measurement of vitamin B12 levels in metformin users.
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Should metformin be used in every patient with type 2 diabetes?
Most patients should receive it, with exceptions. Nevertheless, it is underused.