Ankylosing spondylitis
Conference Coverage
Upadacitinib doubles ASAS 40 response vs. placebo in ankylosing spondylitis
ATLANTA – The selective JAK1 inhibitor upadacitinib had a rapid effect, with a clear difference emerging between the treatment and placebo groups...
Commentary
More studies like VERVE needed to test live vaccines in special populations
“This study was narrow in nature and we certainly need more information on the safety of Zostavax with patients on biologics with other mechanisms...
Conference Coverage
Newer IL-17 inhibitors make their case in phase 3 nonradiographic axial spondyloarthritis trials
There appears to be very little to favor either ixekizumab or secukinumab over the other.
Conference Coverage
COAST-X top-line results: Ixekizumab improves nonradiographic axSpA vs. placebo
ATLANTA – Adding ixekizumab to conventional background medications significantly improved the signs and symptoms of nonradiographic axSpA in the...
News from the FDA/CDC
FDA announces approval of fifth adalimumab biosimilar, Abrilada
Pfizer said that current plans are to launch the drug in the United States in 2023.
Conference Coverage
PREVENT trial shows benefits of secukinumab for nonradiographic axSpA
ATLANTA – The trial of 555 patients “is the largest study done for a biologic agent in nonradiographic axial spondyloarthritis,” said Dr. Atul A....
Conference Coverage
Patients taking TNF inhibitors can safely receive Zostavax
ATLANTA – Investigators found no confirmed varicella infection cases at 6 weeks.
From the Journals
Spinal progression found more often in men with ankylosing spondylitis
Ankylosing spondylitis is more likely to progress in men, individuals with spinal damage, or patients with elevated inflammatory marker levels.
Feature
Trials examine T2T strategy in axial spondyloarthritis
A multinational study has completed enrollment; two others are now recruiting patients.
From the Journals
Ankylosing spondylitis, axial PsA may be two different diseases
“Our study suggests that axial PsA and AS with psoriasis seem to be two different diseases with different genetics, demographics, and disease...
Conference Coverage
Consider centralized pain in patients with rheumatic disease
LAS VEGAS – Every patient with chronic pain should complete a fibromyalgia survey, Dr. Daniel J. Clauw says.