Schizophrenia & Other Psychotic Disorders
Hard Talk
A prescription for de-diagnosing
Similarly to polypharmacy, “polydiagnosing” has negative effects.
Conference Coverage
Schizophrenia patients in long-term facilities benefit from lower-dose antipsychotics
With careful monitoring, some with severe schizophrenia show improved stabilization, social engagement after their long-acting antipsychotic doses...
From the Journals
Motor abnormalities drive decreased function in schizophrenia
Stronger degrees of motor impairment were associated with worse global and social functioning.
Conference Coverage
Social activities may offset psychosis risk in poor communities
Study results showed neighborhood poverty was associated with reduced hippocampal volume, even after controlling for several confounders.
From the Journals
Antipsychotic tied to dose-related weight gain, higher cholesterol
Risperidone is an antipsychotic with a “medium to high metabolic risk profile.”
Conference Coverage
Long-term schizophrenia treatment may not always be necessary
Determining who can go off medications can be challenging, Dr. Stephen Marder told colleagues.
Conference Coverage
High-dose antipsychotics show some benefit in treatment-resistant cases
Patients with severe schizophrenia show decreases in severity and hospitalizations with notably few side effects; but some say stick with...
Conference Coverage
Early metformin minimizes antipsychotic-induced weight gain
The main benefit of metformin is to flatten rather than reverse antipsychotic-induced weight gain.
Out Of The Pipeline
Dexmedetomidine sublingual film for agitation
Approved by the FDA on April 5, 2022, dexmedetomidine sublingual film (Igalmi, manufactured and distributed by BioXcel Therapeutics, Inc., New...
Cases That Test Your Skills
Should clozapine be discontinued in a patient receiving chemotherapy?
Mr. A is diagnosed with leukemia. He has schizophrenia and has long been stable on clozapine. Can this medication be continued, or is the risk of...
Conference Coverage
Telepsychiatry helped maintain standard of schizophrenia care during COVID
For patients with schizophrenia treated with LAIs, the frequency of telepsychiatry visits increased in 46% of the clinics during the pandemic.