Geriatrics
Conference Coverage
Pimavanserin found modestly effective in phase 2 Alzheimer’s psychosis study
BOSTON – The drug’s small improvement in psychotic symptoms may take weeks to appear, but its effect seemed to spare cognition.
Conference Coverage
Amyloid imaging changed management for 80% of patients with uncertain dementia diagnosis
BOSTON – Amyloid imaging can alleviate many of the difficulties in diagnosing some cases of dementia, and using florbetaben looks especially...
Conference Coverage
New BACE1 study launches in the shadow of verubecestat’s demise
An ambitious new clinical trial will investigate a different BACE-inhibiting molecule as an Alzheimer’s preventive in people at high genetic risk...
Conference Coverage
Aducanumab continues to rack up positive numbers in phase 1b open-label extension
BOSTON – Data at 3 years support the relative safety of aducanumab in patients with prodromal or mild Alzheimer’s.
Conference Coverage
Analysis of failed Alzheimer’s trials gives two antiamyloid antibodies new momentum
BOSTON – Researchers are increasing the doses of two antiamyloid drugs in new and existing Alzheimer’s trials based on data from extension studies...
From the Journals
Driving ability of Parkinson’s patients can decline quickly
Findings suggest that health care providers should routinely ask about driving status and make referrals for testing if necessary.
Conference Coverage
VIDEO: Alzheimer’s blood test expected soon
The test is under review for marketing approval.
Conference Coverage
Slow-wave sleep linked to Parkinson’s disease cognition
SAN DIEGO – Study “suggests that interventions to improve sleep might also improve cognitive function in individuals with PD.”
From the Journals
Personality changes may not occur before Alzheimer’s onset
Study authors speculate that self-reported personality changes might not be as reliable as informant report.
Conference Coverage
PRIDE study supports novel approach to ECT for geriatric depression
PARIS – As-needed maintenance electroconvulsive therapy extends the duration of initial remission.
Conference Coverage
Higher BP targets suggested for elderly, cognitively impaired
SAN FRANCISCO – The price of lowering blood pressure in the elderly may be cognitive decline and even Alzheimer’s disease, one expert says.