Depression
Latest News
Positive top-line results for novel psychedelic in major depression
This is the first placebo-controlled efficacy trial of a short-duration psychedelic for depression completed to date.
From the Journals
Psychiatric illnesses share common brain network
The findings highlight the possibility of “potentially developing transdiagnostic treatments based on common neurobiology, not just symptom...
Latest News
Concern grows over ‘medical assistance in dying for mental illness’ law
With the addition of serious mental illness as an eligible category, Canada is on track to have the most liberal assisted-death policy in the...
Evidence-Based Reviews
Evaluation after a suicide attempt: What to ask
Based on our clinical experience, asking these 14 questions can help ensure a safe disposition.
From the Journals
Depression guidelines fall short in characterizing withdrawal
A systematic review highlights the challenges in separating antidepressant withdrawal from depression relapse.
From the Editor
Depression and schizophrenia: Many biological and clinical similarities
Clinicians generally regard major depressive disorder (MDD) and schizophrenia as 2 separate and distinct psychiatric brain disorders.
Cases That Test Your Skills
Subtle cognitive decline in a patient with depression and anxiety
After several months of subtle cognitive decline, Mr. M, age 53, has a panic attack and presents to the ED. He has a history of major depressive...
Commentary
More on psilocybin
I would like to remark on “Psychedelics for treating psychiatric disorders: Are they safe?” (Current Psychiatry, December 2022, p. 14-22, doi:10....
Feature
Guidelines recommend CBT alone for mild acute depression, more options for more severe cases
These nuanced recommendations contrast sharply with the American College of Physicians’ 2016 guideline for depression treatment.
Opinion
Geriatrician advises on use of vitamin D supplementation, lecanemab, and texting for her patients
There is growing awareness of the impact of social isolation on health outcomes, particularly among older adults.
Opinion
Canadian Task Force recommendation on screening for postpartum depression misses the mark
The task force recently recommended against screening with systematic questionnaires, noting that benefits were unclear and not a particular...