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Racial/Ethnic Disparities Among Very Preterm Infants

JAMA Pediatrics; ePub 2018 Sep 10; Janevic, et al

Racial/ethnic disparities in neonatal morbidities among very preterm infants appear to be sizable, but may have been underestimated in previous studies, and may have implications for the future, according to a recent investigation. This population-based retrospective cohort study was conducted in New York City using linked birth certificate, mortality data, and hospital discharge data from January 1, 2010, through December 31, 2014. Racial/ethnic disparities in very preterm birth morbidities were estimated through 2 approaches, conventional analysis and fetuses-at-risk analysis. 582,297 infants were included in this study. Researchers found:

  • Using the conventional approach in the very preterm birth subcohort, black compared with white infants had an increased risk of only bronchopulmonary dysplasia and a borderline increased risk of necrotizing enterocolitis.
  • Hispanic infants had a borderline increased risk of necrotizing enterocolitis, and Asian infants had an increased risk of retinopathy of prematurity.
  • In the fetuses-at-risk analysis, black infants had a 4.40 times higher rate of necrotizing enterocolitis, a 2.73 times higher rate of intraventricular hemorrhage, a 4.43 times higher rate of bronchopulmonary dysplasia, and a 2.98 times higher rate of retinopathy of prematurity.

Citation:

Janevic T, Zeitlin J, Auger N, et al. Association of race/ethnicity with very preterm

neonatal morbidities. [Published online ahead of print September 10, 2018]. JAMA Pediatrics. doi:10.1001/jamapediatrics.2018.2029.