Key clinical point: Breastfed infants who receive formula in the hospital are more likely to wean during the first year, compared with infants who are exclusively breastfed.

Major finding: In one analysis that assumed all bias was controlled through matching, the hazard ratio of weaning across the first year was 6.1 among infants exposed to in-hospital formula feeding. A second, more conservative analysis that corrected for medically necessary supplementation found a hazard ratio of 2.5.

Study details: An analysis of data from over 8,000 infants in the Minnesota Special Supplemental Nutrition Program for Women, Infants, and Children. The researchers used propensity scoring methods to match breastfed infants who received in-hospital formula to those who were exclusively breastfed.

Disclosures: The study authors had no relevant financial disclosures.