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SaO2 vs PaO2 in Cyanotic Patients Evaluated

JAMA Pediatr; ePub Aug 21; Ahmed, et al

Publish date:: August 25, 2017

Measuring oxyhemoglobin saturation (SaO₂) may be a better way to assess oxygenation in cyanotic patients, when compared to arterial oxygen tension (PaO₂), according to a recent study. Details include the following:

Arterial oxygen content is mostly determined by SaO_2.
In patients with several hypoxemia, the degree of change in SaO₂is greater than what occurs in PaO₂.
PaO₂ and SaO₂ tend to move in opposite directions.
Co-oximetry-based SaO₂ is a very precise measurement.
All these observations suggest that SaO₂ is a better choice for evaluating patients with cyanosis.

Citation:

Ahmed H, Tang X, Polizzotti B, et al. Use of oxyhemoglobin saturation, rather than oxygen tension, as a marker of oxygenation in cyanotic patients. [Published online ahead of print Aug 21, 2017]. JAMA Pediatrics. doi:10.1001/jamapediatrics.2017.2213

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