Feature

The Appendix: Is It ’Useless,’ or a Safe House and Immune Training Ground?


 

How Should Doctors View the Appendix?

Even with these mysteries and contradictions, Dr. Vitetta said, a healthy appendix in a healthy body appears to be protective. This is why, he said, when someone is diagnosed with appendicitis, careful assessment is essential before surgery is performed.

“Perhaps an antibiotic can actually help fix it,” he said. A 2020 study published in The New England Journal of Medicine showed that antibiotics may indeed be a good alternative to surgery for the treatment of appendicitis. “We don’t want necessarily to remove an appendix that could be beneficial,” Dr. Smith said.

The many links between the appendix and various diseases mean that doctors should be more vigilant when treating patients who’ve had this organ removed, Dr. Parker said. “When a patient loses an appendix, depending on their environment, there may be effects on infection and cancer. So they might need more regular checkups,” he said. This could include monitoring for IBS and colorectal cancer.

What’s more, Dr. Parker believes that research on the appendix puts even more emphasis on the need to protect the gut microbiome — such as taking probiotics with antibiotics. And while we are still a long way from understanding how exactly this worm-like structure affects various diseases, one thing appears quite certain: The appendix is not useless. “If Darwin had the information that we have, he would not have drawn these conclusions,” Dr. Parker said.

A version of this article first appeared on Medscape.com.

Pages

Recommended Reading

Poop Doesn’t Lie: What Fecal ‘Forensics’ Tells Us About Diet
MDedge Pediatrics
Infant Microbiome Development Minimally Affected by Diet, but Metabolite Profiles Differ
MDedge Pediatrics
Sugar Substitutes Satisfy Appetite, Blunt Insulin Response
MDedge Pediatrics
The Long, Controversial Search for a ‘Cancer Microbiome’
MDedge Pediatrics
High-Quality Diet in Early Life May Ward Off Later IBD
MDedge Pediatrics
Video Games Marketing Food Impacts Teens’ Eating
MDedge Pediatrics
Specialists Are ‘Underwater’ With Some Insurance-Preferred Biosimilars
MDedge Pediatrics
Gene Tests Could Predict if a Drug Will Work for a Patient
MDedge Pediatrics
FDA Grants New Pediatric Arthritis Indications for Upadacitinib
MDedge Pediatrics
Celiac Disease: Five Things to Know
MDedge Pediatrics