Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Promising efficacy with adavosertib in uterine serous carcinoma

Key clinical point: Adavosertib monotherapy showed efficacy against recurrent uterine serous carcinoma.

Major finding: The overall response rate was 30% among 21 patients for whom data were available.

Study details: An interim analysis of data on 21 of 35 planned patients in a phase 2 trial.

Disclosures: Dr. Liu disclosed ties with AstraZeneca, which supported the trial, as well as Merck and other companies.

Citation:

Liu JF et al. SGO 2020, Abstract 7.