Breast Cancer
Medicolegal Issues
Delayed diagnosis of breast cancer: $15M award
From the Journals
Inherited mutations drive 12% of Nigerian breast cancer
Mutations in four breast cancer risk genes cause about one in eight cases of the malignancy in Nigerian women.
From the Journals
Variants in five genes signal TNBC risk
Risks for triple-negative breast cancer associated with pathogenic variants in five genes ranged from about 5.5-fold to nearly 17-fold.
From the Journals
RT linked with better survival in DCIS
Lumpectomy plus radiotherapy is associated with a significant reduction in breast cancer mortality versus lumpectomy or mastectomy alone.
From the Journals
Herceptin linked to doubling of HF risk in women with breast cancer
Most patients are not receiving the frequency of guideline-recommended cardiac screening, study finds.
Conference Coverage
Lower CTC count IDs indolent MBC disease subset
A CTC count less than 5 per 7.5 mL of blood in MBC patients indicates an indolent disease subset, pooled data from two large cohorts show.
News
FDA expands indication for ribociclib for advanced breast cancer
Approval of the CDK 4/6 inhibitor was expanded to include the treatment of pre/perimenopausal women with HR-positive, HER2-negative, in...
Conference Coverage
Trastuzumab biosimilar is equivalent on central review
CHICAGO – In a 20-country neoadjuvant trial, findings when tissue was centrally reviewed differed somewhat from those when tissue was reviewed...
Expert Commentary
Does hormone therapy increase breast cancer risk in BRCA1 mutation carriers?
No. In a prospective study that followed 872 BRCA1 carriers after oophorectomy for a mean follow-up of...
From the Journals
Higher BMI tied to lower breast cancer risk in women before menopause
The effect was strongest in women aged 18-24 years, when it spanned breast cancer subtypes.
Conference Coverage
TAILORx marks major advance for precision medicine in breast cancer
CHICAGO – Practice-changing data show that most women with HR-positive, HER2-negative, early-stage breast cancer who have an intermediate...