Misoprostol might reduce pain in postmenopausal women, according to this systematic review. However, the investigators note, “there is no high-quality evidence that giving misoprostol before outpatient hysteroscopy reduces the pain experienced by women of reproductive age.”
Cooper NAM, Smith P, Khan KS, Clark TJ. Does cervical preparation before outpatient hysteroscopy reduce women’s pain experience? A systematic review. BJOG. 2011;118(11):1292–1301.
EXPERT COMMENTARY
Linda D. Bradley, MD Professor of Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University; Vice Chairman, Obstetrics, Gynecology, and Women’s Health Institute; and Director, Center for Menstrual Disorders, Fibroids and Hysteroscopic Services, Cleveland Clinic, Cleveland, Ohio. Dr. Bradley serves on the OBG Management Board of Editors.
