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Gout Prophylaxis and Disease Burden

J Rheumatol; ePub 2016 Mar 15; Schlesinger, Etzel, et al

Gout prophylaxis was significantly more common in patients with a higher disease burden and activity, which is in agreement with the American College of Rheumatology guidelines, according to a study of 1,049 patients with gout, including 42% receiving prophylaxis and 58% not receiving prophylaxis. Researchers found:

• Drugs most commonly used for prophylaxis were colchicine (78%), and nonsteroidal anti-inflammatory drugs (32%).

• Prophylaxis drug combination was used by 10.2% of patients.

• Patients receiving prophylaxis were more likely to have a gout duration of ≤1 year, ≥1 flare in the year prior to enrollment, ≥1 healthcare uses in the last year, have tophi, report pain, and have disease activity >10 vs patients not receiving prophylaxis.

Citation: Schlesinger N, Etzel CJ, Greenberg J, Kremer J, and Harrold LR. Gout prophylaxis evaluated according to the 2012 American College of Rheumatology Guidelines: Analysis from the CORRONA Gout Registry. [Published online ahead of print March 15, 2016]. J Rheumatol. doi:10.3899/jrheum.150345.