Key clinical point: In patients with psoriatic arthritis (PsA), a high dietary acid load (DAL), evaluated through potential renal acid load (PRAL) and net endogenous acid production (NEAP), was associated with increased disease activity and inflammation.
Major finding: The mean Disease Activity Index for PsA scores were higher in patients with PsA who had high vs low PRAL (19.8 vs 14.0; P = .006) and high vs low NEAP (20.3 vs 13.5; P = .001). In addition, patients in the high vs low PRAL and NEAP groups had significantly higher C-reactive protein levels ( P = .024 and P = .020, respectively), indicating increased inflammation.
Study details: Findings are from a cross-sectional study that included 58 patients with overweight or obesity and a diagnosis of PsA.
Disclosures: This study did not disclose any funding. The authors declared no conflicts of interest.
Source: Öteleş S et al. The dietary acid load is associated with disease severity in psoriatic arthritis. Mod Rheumatol. 2023 (Nov 10). doi: 10.1093/mr/road107