Key clinical point: No appreciable association was observed between a history of migraine or its subtypes and an increase in the risk for COVID-19, including hospitalization for COVID-19, in older women.
Major finding: No significant association was observed between a history of migraine and the risk of developing COVID-19 (odds ratio [OR] 1.08; 95% CI 0.95 -1.22) or being hospitalized for COVID-19 (OR 1.20; 95% CI 0.86 -1.68) among older women. Similarly, other migraine statuses, including migraine with aura, showed no association with the risk for COVID-19.
Study details: This prospective cohort study included 16,492 women (age ≥ 45 years) enrolled in the Women’s Health Study, of whom 28.9% had a history of migraine and 7.7% reported positive SARS-CoV-2 test results, a diagnosis of COVID-19, or hospitalization for COVID-19.
Disclosures: The Women’s Health Study was funded by grants from the US National Cancer Institute and the US National Heart, Lung, and Blood Institute. T Kurth declared receiving research grants and personal compensation from various sources. The other authors declared no conflicts of interest.
Source: Rist PM et al. History of migraine and risk of COVID-19: A cohort study. Am J Med. 2023 (Aug 18). doi: 10.1016/j.amjmed.2023.07.021