Key clinical point: Nearly 24% of patients with multiple sclerosis (MS) experience migraine, with the odds of migraine occurrence being approximately 2-fold higher in patients with MS compared with control individuals.
Major finding: The overall prevalence rate of migraine among patients with MS was 0.24 (95% CI 0.21 -0.28). Moreover, patients with MS vs control participants without MS had a ~2-fold greater risk of experiencing migraine (odds ratio 1.96; 95% CI 1.20 -3.20).
Study details: This meta-analysis of 35 studies included 279,620 patients with MS and 279,603 control participants without MS.
Disclosures: This study did not receive any funding. The authors declared no conflicts of interest.
Source: Mohammadi M et al. The association between multiple sclerosis and migraine: A meta-analysis. Mult Scler Relat Disord. 2023;79:104954 (Aug 30). doi: 10.1016/j.msard.2023.104954