Key clinical point: The six active ingredients (notably avobenzone) in four sunscreen products were systemically absorbed after a single application.

Major finding: The geometric mean plasma concentrations were greater than 0.5 ng/mL for avobenzone, oxybenzone, octocrylene, homosalate, octisalate, and octinoxate.

Study details: The data come from a randomized clinical trial of 48 adults with Fitzpatrick skin types II, III, or IV.

Disclosures: The study was supported by the Food and Drug Administration. The researchers had no financial conflicts to disclose.