Adaptive, computer-based cognitive remediation accessed from home can improve cognitive functioning in multiple sclerosis (MS), according to a recent study. Researchers hypothesized that training at home with an adaptive online cognitive training program would have greater cognitive benefit than ordinary computer games in cognitively-impaired adults with MS and conducted a double-blind, randomized, active-placebo-controlled trial. Participants with MS were recruited and randomly assigned to either the adaptive cognitive remediation (ACR) program or active control of ordinary computer games for 60 hours over 12 weeks. They found:

• Participants in the ACR (n=74) vs active control (n=61) training program had significantly greater improvement in the primary outcome of cognitive functioning, despite greater training time in the active control condition.
• Furthermore, this telerehabilitation approach allowed for rapid recruitment and high compliance, and can be readily applied to other neurological conditions associated with cognitive dysfunction.