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Head Trauma, Autoimmune Diseases: No Link with MS
Neuroepidemiol; ePub 2018 Nov 26; Abdollahpour, et al
Lifetime histories of head trauma, as well as 9 investigated autoimmune diseases, are not associated with increased risk of multiple sclerosis (MS), according to a recent study. Researchers conducted a population-based incident case-control study with 547 incident MS cases and 1,057 general population controls from August 7, 2013, to February 17, 2015. Multiple logistic regression models were used for estimating the adjusted odds ratios. They found:
- Lifetime history of head trauma was not significantly associated with risk of MS after adjustment for well-known confounders (OR 1.24).
- Similarly, there was no statistically significant association between cumulative numbers of head injury and MS (OR 1.02).
- A history of autoimmune disease did not increase the risk of MS.
- Similarly, the cumulative number of autoimmune diseases is not significantly associated with the risk of MS.
Abdollahpour I, Lizarraga AA, Nedjat S, Mansournia MA, Weinstock-Guttman B. Medical history and multiple sclerosis: A population-based incident case-control study. [Published online ahead of print November 26, 2018]. Neuroepidemiol. doi:10.1159/000494257.