The Consortium of Multiple Sclerosis Centers (CMSC) Task Force has updated its standardized MRI protocol and clinical guidelines for the diagnosis and follow-up of MS. The revision to the 2006 MRI protocols include the following changes:
• an emphasis on 3D sequences of brain MRI
• a specific monitoring protocol for progressive multifocal leukoencephalopathy (PML)
• an optional orbit MRI protocol for severe optic neuritis
Key changes to the 2006 clinical guidelines include:
• specific timing for using brain MRIs to monitor response to disease-modifying therapies
• timing of brain MRIs for PML surveillance
• inclusion of radiologic isolated syndrome
The updated guidelines also include new evidence regarding the value of MRI changes in determining treatment effectiveness.
Citation: 2015 Revised CMSC MRI Protocol and Guidelines. CMSC website. http://c.ymcdn.com/sites/www.mscare.org/resource/collection/9C5F19B9-3489-48B0-A54B-623A1ECEE07B/MRIprotocol2015.pdf. Updated April 2015. Accessed April 10, 2015.