Literature Review

Surgery or Medical Management for Refractory Pediatric Epilepsy?


 

Ten patients in the medical-therapy group had physical injuries associated with seizures (eg, cuts, burns, and fractures). One patient had an adverse event associated with an antiepileptic drug, and autistic features developed in another patient. No deaths occurred in either group.

One study limitation was that patients included in this trial underwent many types of epilepsy surgeries to treat various underlying pathologic causes of seizures. Another limitation was that there was an overrepresentation of hypothalamic hamartomas, compared with some other series, said the researchers.

—Erica Tricarico

Suggested Reading

Dwivedi R, Ramanujam B, Chandra PS, et al. Surgery for drug-resistant epilepsy in children. N Engl J Med. 2017;377(17):1639-1647.

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