Neurology
News
Bevacizumab Combinations Effective in Phase II Glioblastoma Trials
Major Finding: A chemoradiation regimen with bevacizumab, temozolomide, and irinotecan increased progression-free and overall survival by about 6...
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Thrombolysis Effective, Safe in Patients 80 and Older
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Cediranib Falls Short in Phase III Glioblastoma Trial
Major Finding: Progression-free survival did not show a statistically significant advantage of cediranib monotherapy (median, 92 days; P = .889)...
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Stroke History Did Not Change Safety, Effectiveness of Dabigatran
Major Finding: The primary outcome of stroke or systemic embolism occurred at similar rates among patients with a previous stroke or TIA taking...
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Vitamin E May Help Traumatic Brain Injury Patients
Major Finding: The in-hospital death rate from traumatic brain injury following a course of high doses of vitamin E was 20%, compared with 30% and...
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Short Amicar Protocol May Cut Aneurysm Rerupture Rate
Major Finding: Aneurysms reruptured in 6 (2%) of 244 patients who received the antifibrinolytic drug Amicar, compared with 14 (7%) of 210 patients...
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FDA Panels Vote on Safety of IV Seizure Drugs
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Paricalcitol Reduced Residual Renal Risk in Diabetic Nephropathy Patients
Major Finding: Of 281 patients randomized to receive either placebo, 1 mcg, or 2 mcg of paricalcitol for 24 weeks along with their usual care for...
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Off-Label Use of rFVIIa Linked to Arterial Thromboembolic Events
Major Finding: The rate of arterial thromboembolic events, particularly coronary arterial thromboembolic events, is approximately three times...
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Brain MRI Predicts Stroke Age, May Lead to More tPA Use
Major Finding: A FLAIR ratio cutoff of 7% on MRI identified patients imaged within 3 hours of stroke onset with 90% sensitivity and 92%...