Immunology
From the Journals
High allele level linked to lamotrigine-induced SCAR
Could higher frequency of alleles associated with drug-induced severe cutaneous adverse reactions be specific to ethnicity?
Conference Coverage
Flu shots may spark immune adverse events in PD-1 blockade for NSCLC
GENEVA – More than half of patients who had received a trivalent influenza vaccine in a small study had immune-related adverse events.
From the Journals
Skin testing and decision support can clarify penicillin allergy
Many patients who report penicillin allergy actually can safely take it; skin testing and computerized decision support can identify them.
News
FDA: Recall of select EpiPen products
Meridian Medical Technologies has issued a voluntary recall for 13 lots of EpiPen products, according to the U.S. Food and Drug Administration.
Conference Coverage
Oral agent found promising for subset of chronic rhinosinusitis patients
ATLANTA – Patients with chronic rhinosinusitis tolerated dexpramipexole well and showed robust and tissue eosinophil–lowering activity.
Conference Coverage
Survey finds chronic rhinosinusitis common, burdensome
ATLANTA – Results from a large cross-sectional survey of adults who meet diagnostic symptom criteria for chronic rhinosinusitis reveal that most...
Conference Coverage
Uptick found in severe allergy shot reactions
ATLANTA – There has been an uptick in reports of severe grade 4 reactions to subcutaneous allergen immunotherapy for reasons that are not yet...
From the Journals
Lanadelumab reduced hereditary angioedema attacks by 88%-100%
Lanadelumab reduced attacks of hereditary angioedema with C1 inhibitor deficiency by 88%-100%.
News
EpiPen cost increases far exceed overall medical inflation
Total Medicare part D spending on EpiPen auto-injectors rose from $7.0 million in 2007 to $87.9 million in 2014, according to the Kaiser Family...
Conference Coverage
ACOS definitions under fire
Key clinical point: A study comparing current definitions of Asthma-COPD Overlap Syndrome (ACOS) provoked criticism of the very concept. Major...
Conference Coverage
Benralizumab reduces exacerbations in pivotal severe asthma trials
Key clinical point: Benralizumab significantly reduced the annual exacerbation rate (AER), improved lung function, and reduced asthma symptoms....