Geriatrics
Conference Coverage
Long-term cholinesterase inhibition may slow cognitive decline – and more
BOSTON – New data suggest the drugs also reduce risk of heart attack, stroke, and all-cause mortality.
Conference Coverage
Pimavanserin found modestly effective in phase 2 Alzheimer’s psychosis study
BOSTON – The drug’s small improvement in psychotic symptoms may take weeks to appear, but its effect seemed to spare cognition.
Conference Coverage
Unblinded data show extent of verubecestat’s failure in mild-moderate Alzheimer’s
BOSTON – No benefit was seen in any endpoint, in any subgroup.
Conference Coverage
Amyloid imaging changed management for 80% of patients with uncertain dementia diagnosis
BOSTON – Amyloid imaging can alleviate many of the difficulties in diagnosing some cases of dementia, and using florbetaben looks especially...
Conference Coverage
New BACE1 study launches in the shadow of verubecestat’s demise
An ambitious new clinical trial will investigate a different BACE-inhibiting molecule as an Alzheimer’s preventive in people at high genetic risk...
Conference Coverage
Nebulized glycopyrrolate improves lung function in COPD
TORONTO – Glycopyrrolate, a novel nebulized long-acting muscarinic antagonist (LAMA) in development, was well-tolerated and significantly improved...
Conference Coverage
Aducanumab continues to rack up positive numbers in phase 1b open-label extension
BOSTON – Data at 3 years support the relative safety of aducanumab in patients with prodromal or mild Alzheimer’s.
Conference Coverage
Analysis of failed Alzheimer’s trials gives two antiamyloid antibodies new momentum
BOSTON – Researchers are increasing the doses of two antiamyloid drugs in new and existing Alzheimer’s trials based on data from extension studies...
From the Journals
Driving ability of Parkinson’s patients can decline quickly
Findings suggest that health care providers should routinely ask about driving status and make referrals for testing if necessary.
Conference Coverage
VIDEO: Alzheimer’s blood test expected soon
The test is under review for marketing approval.
From the Journals
Study: Varicose vein procedures should be offered to patients 65 years and older
Benefits of varicose vein procedures were similar for younger patients and those over 65 years of age.