Gastroenterology
News
Sofosbuvir combo effective in unresponsive HCV
Major Finding: Sixty-eight percent of patients who took sofosbuvir plus weight-based doses of ribavirin and 48% of those who took sofosbuvir plus...
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Consensus statement: Data on cancer, pancreatitis do not warrant change in prescribing of antihyperglycemics
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Vedolizumab shows promise in Crohn’s, ulcerative colitis
Major finding: Six-week clinical response with vedolizumab vs. placebo for ulcerative colitis: 47.1% vs. 25.5%; 6-week clinical remission with...
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Colorectal cancer risk increased with bariatric surgery
Major finding: The risk of colorectal cancer increased by 60% among obese patients, a mean of 7 years after bariatric surgery but was only...
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Interferon-free regimens effective for hepatitis C virus genotype 1
Major finding: The primary efficacy endpoint – a sustained virologic response (an undetectable plasma level of HCV RNA) 12 weeks after the...
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Study identifies distinct microbiome in Crohn’s intestinal submucosa
Major finding: Total bacteria counts and evidence of certain bacterial populations were significantly more common in the intestinal submucosa of...
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Preventing a second bout of acute pancreatitis
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Depression, some antidepressants linked to high C. difficile risk
Major finding: Older adults with a history of major depressive disorder were 36% more likely to develop Clostridium difficile–associated diarrhea...
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Splenectomy mortality risk similar for malignant and benign disease
Major finding: Following elective splenectomy, the rate of overall complications was significantly higher for patients with malignant vs. benign...
News
Biopsy results in celiac disease patients may predict cancer risk
Major finding: The risk of developing a lymphoproliferative malignancy (LPM) was about twofold higher among patients with celiac disease who had...