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Cocaine & Marijuana Use in Young Adults with MI
J Am Coll Cardiol; ePub 2018 Mar 10; DeFilippis, et al
Cocaine and/or marijuana use is present in 1 of 10 patients with a myocardial infarction (MI) aged ≤50 years and is associated with worse all-cause and cardiovascular (CV) mortality, a recent study found. The retrospective study analyzed records of patients presenting with a Type 1 MI at ≤50 years at 2 academic hospitals from 2000 to 2016. Researchers determined:
- Among 2,097 patients with Type 1 MI (mean age 44±5.1 years, 19.3% female, 73% white) with median follow-up of 11.2 years, 224 (10.6%) used cocaine and/or marijuana.
- Substance abuse was associated with significantly higher CV and all-cause mortality despite lower prevalence of traditional risk factors.
- Those with substance use had significantly lower rates of diabetes and hyperlipidemia but were significantly more likely to use tobacco.
- Young adults with MI should be screened for substance abuse to stratify risk.
Citation:
DeFilippis EM, Singh A, Divakaran S, et al. Cocaine and marijuana use among young adults presenting with myocardial infarction: The Partners YOUNG-MI Registry. [Published online ahead of print March 10, 2018]. J Am Coll Cardiol. doi:10.1016/j.jacc.2018.02.047.