Researchers at the Columbia University Mailman School of Public Health have identified distinct immune changes in patients diagnosed with chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME/CFC). These findings provide the most definitive evidence to date that the condition is biologically based, not psychological. The large, multicenter study presents evidence of increased amounts of certain immune molecules called cytokines in patients who had the disease three years or less that were not present in those who had the disease a longer period of time or who did not have the disease.
http://www.mailman.columbia.edu/news/chronic-fatigue-moves-out-shadows