Dr. Lees and six of his seven coauthors disclosed having received grants, honoraria, or other forms of financial support from Boehringer Ingelheim, the German manufacturer of alteplase, along with other pharmaceutical companies. They noted that the SITS and VISA registries, from which all their data were derived, receive ongoing funding from Boehringer Ingelheim. Dr. Derex disclosed no current support relevant to the accompanying editorial, but acknowledged past honoraria from Boehringer Ingelheim and work as an investigator on trials sponsored by that company.