Anemia
Conference Coverage
ASH: Gene therapy reduces transfusion needs in beta-thalassemia major
Lentiviral-based gene therapy can lead to transfusion independence in some patients with beta-thalassemia major.
News
Antibiotics to reduce microbiota may improve treatment of sickle-cell disease
The body’s microbiota was found to regulate the aging of circulating neutrophils, a discovery that points the way to easily and markedly improve...
News
More than 75% with sickle cell crises don’t get hydroxyurea
Key clinical point: More than 75% of adults with sickle cell anemia who have frequent pain crises fail to get hydroxyurea therapy as recommended....
News
Stem cells from sickle cell disease patients used to generate gene-corrected cells
Guidelines
NHLBI expert panel issues guideline on sickle cell disease
Major finding: The two most widely available disease-modifying therapies for SCD, hydroxyurea and long-term transfusions, are underused, in large...
Conference Coverage
Sickle cell crises curtailed with experimental cellular adhesion inhibitor
Major finding: The mean time to resolution of vaso-occlusive crisis in patients with sickle cell disease was 103 hours for patients treated with...